Creatinine CAS NO.60-27-5

CAS :60-27-5 Sports Supplement Food Additive  Creatinine
Product Name:    Creatinine
Synonyms:    
2-Amino-1-methylimidazolidin-4-one; 2-Imino-1-methylimidazolidin-4-one; 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one; 2-amino-1-methyl-1,5-dihydro-4H-imidazol-4-one; 2-amino-3-methyl-5-oxo-4,5-dihydro-1H-imidazol-3-ium
CAS RN.:    
60-27-5
EINECS:    200-466-7
Molecular Weight:    114.1253
Molecular Formula:    C4H8N3O
Melting Point(ºC):    255ºC
Water Solubility:    SOLUBLE
Creatinine  is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass).

Creatine is most commonly used for improving exercise performance and increasing muscle mass in athletes and older adults. There is some science supporting the use of creatine in improving the athletic performance of young, healthy people during brief high-intensity activity such as sprinting. Because of this, creatine is often used as a dietary supplement to improve muscle strength and athletic performance. In the U.S., a majority of sports nutrition supplements, which total $2.7 billion in annual sales, contain creatine.

Creatine use is allowed by the International Olympic Committee, National Collegiate Athletic Association (NCAA), and professional sports.

In addition to improving athletic performance and muscle strength, creatine is taken by mouth for creatine deficiency syndromes that affect the brain, aging, bone density, chronic obstructive pulmonary disease (COPD), congestive heart failure (CHF), depression, diabetes, exercise tolerance, fibromyalgia, Huntington's disease, disease that cause inflammation in the muscles (idiopathic inflammatory myopathies), Parkinson's disease, diseases of the muscles and nerves, multiple sclerosis, muscle atrophy, muscle cramps, breathing problems in infants while sleeping, head trauma, Rett syndrome, an eye disease called gyrate atrophy, inherited disorders that affect the senses and movement, schizophrenia, muscle breakdown in the spine, and recovery from surgery. It is also taken by mouth to slow the worsening of amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), osteoarthritis, rheumatoid arthritis, McArdle's disease, and for various muscular dystrophies.

People apply creatine to the skin for aging skin.
 

How does it work

Creatine is involved in making the energy muscles need to work.

Vegetarians and other people who have lower total creatine levels when they start taking creatine supplements seem to get more benefit than people who start with a higher level of creatine. Skeletal muscle will only hold a certain amount of creatine; adding more won't raise levels any more. This "saturation point" is usually reached within the first few days of taking a "loading dose."