Ibogaine HCL, Iboga HCL CAS NO.12629-01-5

boga, which has been translated as “to care for”1 or “to heal,” is the common name of a group of perennial shrubs that belong to the Apocynaceae family, which are typically found in the understory of tropical forests in the Congo Basin.2 The name usually refers to Tabernanthe iboga, but can also include Tabernanthe manii, or other varieties, which are not always botanically distinguished.3 There are reported to be a total of seven common identified varieties of iboga found throughout Gabon, where it is most prolific.4 Some data suggests that there could be as many as 650 recorded variations in the Tabernanthe genus.5

In the Central West African rainforest, iboga has a history of traditional use in rituals of healing and rights of passage that stretches back for millennia. Its use originated with the pygmies, or forest people, who later shared their knowledge with the Bantu population of Gabon. This exchange led to the development of Bwiti around the late 19th century. While remaining central to Gabonese culture, more recently, Bwiti temples have spread to some of the surrounding regions such as Equatorial Guinea, Cameroon, the Congo, and Zaire.6

Mature iboga trees often grow to about 1.5 meters in height and diameter, but older specimens have been known to grow to the size of small trees, sometimes 10 meters in height, under certain circumstances. While there are differentiations between varieties, iboga is best characterized by its small five-petaled flowers and distinctive inedible orange fruits.

Iboga is the best known and most concentrated plant source for ibogaine, as well as 11 other alkaloids.7 Lower doses are traditionally used to combat fatigue, and as an aphrodisiac. Larger doses are used ritually in initiation. In occidental society, ibogaine therapy has several applications, including as an aid to psychotherapy and in the treatment of substance use disorders, especially for opiate use disorders. Some of the other iboga alkaloids have independently been shown to interrupt substance use disorders.8

ibogaine is a psychoactive alkaloid naturally occurring in the West African shrub iboga. While ibogaine is a mild stimulant in small doses, in larger doses it induces a profound psychedelic state. Historically, it has been used in healing ceremonies and initiations by members of the Bwiti religion in various parts of West Africa. People with problem substance use have found that larger doses of ibogaine can significantly reduce withdrawal from opiates and temporarily eliminate substance-related cravings.

Use to treat addiction problems

Recent reports about the sustainability of Tabernanthe iboga and related species may be experiencing over-harvesting, and may also be affected by a number of other environmental and social factors, which may threaten its population in its natural habitat.

CONTACT